Generalized Methodology for Array Processor Design of Real-time Systems

Many techniques and design tools have been developed for mapping algorithms to array processors. Linear mapping is usually used for regular algorithms. Large and complex problems are not regular by nature and regularization may cause a computational overhead which prevents the ability to meet real-time deadlines. In this paper, a systematic design methodology for mapping partially-regular as well as regular Dependence Graphs is presented. In this approach the set of all optimal solutions is generated under the given constraints. Due to nature of the problem and the tight timing constraints of real-time systems the set of alternative solutions is limited. An image processing example is discusse

Two-level pipelined systolic array graphics engine

The authors report a VLSI design of an advanced systolic array graphics (SAG) engine built from pipelined functional units which can generate realistic images interactively for high-resolution displays. They introduce a structured frame store system as an environment for the advanced SAG engine and present the principles and architecture of the advanced SAG engine. They introduce pipelined functional units into this SAG engine to meet the performance requirements. This is done by a formal approach where the original systolic array is represented at bit level by a finite, vertex-weighted, edge-weighted, directed graph. Two architectures built from pipelined functional units are described. A prototype containing nine processing elements was fabricated in a 1.6-¿m CMOS technolog

Neuroprotective effect of renin angiotensin system blockers on experimentally induced Alzheimer’s disease in rats

Background: Alzheimer’s disease (AD) is a major world-wide health problem. Much evidence points to a link between hypertension and AD. However, the exact effects of different antihypertensive drugs on AD need to be more assessed. The aim was to evaluate and compare the possible effects of perindopril, and candesartan on cognitive impairment, oxidative stress markers, and brain concentrations of amyloid beta-peptide (Aβ-P) in a rat model of induced dementia.Methods: Thirty-two adult male Wistar rats were distributed among 4 groups; (1) normal controls; (2) rats with dementia induced by intracerebroventricular administration of streptozotocin (ICV-STZ) and received no treatment; (3) ICV-STZ rats treated orally with perindopril for 3 weeks; and (4) ICV-STZ rats treated orally with candesartan for 3 weeks. The assessed parameters were spatial memory by Morris Water Maze test, brain tissue level of total antioxidant capacity (TAC), reduced glutathione (GSH), lipid peroxidation product (malondialdehyde [MDA]), and Aβ-P.Results: Both perindopril and candesartan attenuated STZ-induced memory impairment, caused a significant increase in TAC and GSH levels, reduced MDA levels, whereas only candesartan significantly reduced Aβ-P levels.Conclusions: This study reports that candesartan and perindopril can reverse the free radical induced damages and resultant memory defects, and may suggest candesartan as worthy drugs for prevention of Aβ-P deposition in this animal model of AD

The Lateral Distortional Buckling of I-Plate Girders

This paper presents a numerical study for lateral distortional buckling of I-plate girders (LDBIPGs) by using the general-purpose finite element package ABAQUS (version 6.13) software. 3-D finite element (FE) models for simply supported IPGs subjected to two cases of loading are built. The first case of loading was uniform end moment that was introduced by a couple of forces applied at the top and bottom flanges of the IPGs. The second case of loading was a concentrated load at the shear center in the mid-span. First, shell finite element models are validated by comparing the FE critical bending moment (������,����) by the critical bending moment in EC3 code (������,��,������). The results indicate that the ������,���� was in good agreement with ������,��,������. Secondly, a preliminary analysis is conducted to the relative girder slenderness (��) where the LDB too place. Finally, a parametric study is carried out on simply supported IPGs regarding to the span length, the flange cross-section dimensions and the thickness of the web. The results showed that increasing the length of girders decreases ������.���� and increase in the bending coefficient factor (����). Also, decreasing in the web plate slenderness ratio (��������⁄) works on increasing in ������.���� values and ����. The results also showed that the increasing in the thickness of flange increases ������.���� and increase the value of ���� with small value. As a result of parametric study, the mean value and standard deviation of ���� for LDB mode are 1.16 and 0.08 respectively for �� limits (90:130). For �� limits (131:175), the mean value and standard deviation of ���� are 1.27 and 0.03 respectively. As for �� limits (176:221), the mean value and standard deviation of ���� are 1.32 and 0.02 respectively

Further Results on the Heat Transfer to Low-Prandtl Number Fluids in Pipes

Numerical predictions have been made of heat transfer to low-Prandtl-number fluids in pipes with constant wall heat flux. The turbulence model employed is of the two-equation (k-)c kind in the core and the one-equation (k) kind in the near-wall region. Fluids with Prandtl numbers in the range 0.007-0.045 have been examined, in the Reynolds range from 7600 to 106. Temperature profiles and Nusselt numbers are in fairly good agreement with experiments on fully developed flow. Nusselt numbers for the thermal entrance region are found to be in reasonable agreement with the experimental results, which, however, display a large scatter

THE ROLE OF ANTICOAGULANTS AND ANTIPLATELETS IN PROPHYLAXIS AND/OR TREATMENT OF SEVERE SARS-COV-2 INFECTION

Severe acute respiratory syndrome coronavirus-2(SARAS-COV-2) was reported firstly in China by the end of  2019 then disseminated vigorously worldwide  and in 2020 reported by WHO as pandemic disease. It is associated by many symptoms, however; high incidence of thrombotic events was strongly correlated with SARAS-COV-2. Exploring anticoagulants to be added as thromboprophylaxis for Covid 19 patients become a must. Many options for thromboprophylaxis are available including anticoagulants, antiplatelets and fibrinolytics which were illustrated in this mini review.                       Peer Review History: Received 19 January 2021; Revised 3 February; Accepted 24 February, Available online 15 March 2021 Academic Editor: Essam Mohamed Eissa, Beni-Suef University, Egypt, [email protected] Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Cecilia Nwadiuto Amadi, University of Port Harcourt, Port Harcourt Rivers State, Nigeria, [email protected] Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, [email protected] Similar Articles: COVID-19: PHARMACOLOGICAL AND THERAPEUTIC APPROACHES USE OF COLCHICINE TO COUNTERACT THE STRONG HYPERINFLAMMATORY STATE INDUCED BY SARS-COV-2 THE RISKS AND ADVANTAGES OF ANTI-DIABETES THERAPY IN THE POSITIVE COVID-19 PATIENT EUCALYPTUS ESSENTIAL OIL; AN OFF-LABEL USE TO PROTECT THE WORLD FROM COVID-19 PANDEMIC: REVIEW-BASED HYPOTHESES SUDANESE EXPERIENCE OF HERBAL FORMULAS USED DURING COVID-19 INFECTION TRADITIONAL TO RECENT APPROACHES IN HERBAL MEDICINE THERAPY OF COVID-1